Future, Ongoing, and Past Projects
Ongoing Projects
2020-2023: European Commission – ERA HDHL PREVNUT – Project: AMBROSIA – Microbiota-Inflammation-Brain axis in heart failure: new food, biomarkerS and AI Approach for the prevention of undernutrition in Older (Coordinator)
2021-2024: European Commission – JOINT RESEARCH CENTRE – Collaborative Doctoral Partnership (CDP) – Health promotion and prevention of non-communicable diseases (NCDs) – Project – From polyp to colorectal cancer: the impact of the interplay between T cells and gut microbiota in obese patients (Partner)
2021-2025: European Commission – COST Action CA20101 – Project – Plastics monitoring detection remediation recovery – PRIORITY (Partner)
2022-2024: Italian National Research Council (CNR) – Project – Tackling COronaViruses-related diseases by developing viral Protease Inhibitors – COVPI (Partner)
2022-2025:European Union – NextGenerationEU under PNRR 2022 Large Extended Partnership Projects “Neuroscience and neuropharmacology” – A multiscale integrated approach to the study of the nervous system in health and disease (MNESYS) (Partner)
2022-2025: Italian Ministry of Health “Nutraceutics, nutrigenomics and functional foods”, Action 5.1 “Creation of an action program to fight malnutrition in all its forms and for the diffusion of the principles of the Mediterranean diet” – Project – FUNCTIONAL FOODS ITALY NETWORK (Partner)
2022-2025: Ministry of University and Research (PNRR) ITALY – Project Tuscany Health Ecosystem (THE) Project by prof. Amedei for the sector – Preventive and predictive medicine (spoke leader UNIFI; Partnership affiliati UNISI, UNIPI) – Microbiota-Inflammation-Brain axis in heart failure and inflammatory bowel disease: undernutrition prevention biomarkers and AI Approach (Partner)
2022-2025: University of Florence “Public-private partnerships aimed at implementing “problem-driven” projects focused on central themes in European programming and consistent with the PNR” – Project – Microbiota Immunity Axis: Functional food for the modulation of inflammation in gastrointestinal pathologies (SOURCES ) (Principal Investigator)
2023-2025: Italian Ministry of Health under PNRR M6/C2_CALL 2022 – Genetics and Environment intersection In the Amyotrophic Lateral Sclerosis – FrontoTemporal Dementia spectrum: an Italian Twins cohort study with a Multi-Omics approach (GENIALITY) (Partner)
2023-2025: Italian Ministry of University and Research under PRIN 2022 – Plaiority – Nano/microplastics effects on human health: transcriptional profiles, molecular pathways and inflammatory response associated with cell biology and microbiota dysfunction (Coordinator)
2023-2025: Italian Ministry of University and Research under PRIN PNRR 2022 – MysticALS –Microorganisms, toxins and immunity intersection In amyotrophic lateral Sclerosis and frontotemporal dementia: targeting disease Heterogeneity (Partner)
2023-2025: ESA (European Space Agency) – Project – Neuroendocrine-metabolic-inflammatory and infection-proneness profile testing before and after long-term underwater and extraterrestrial missions – NEPTUNE(ISS-PP) (Partner)
2023-2025: ESA (European Space Agency) – Project – Neuroendocrine-metabolic-inflammatory and infection-proneness Profile Testing before, during and after short-term underwater and extraterrestrial missions – NEPTUNE(ISS-SDM) (Partner)
2023-2025: University of Florence – The effect of microplastic on microbiota and immunity-axis (Principal Investigator)
2023-2026: Italian Ministry of Health – BANDO RICERCA FINALIZZATA 2021- Neurosteroids against Neuroinflammation: a way to fight Neurodegeneration in Amyotrophic Lateral Sclerosis? (Neural Stop) (Partner)
2024-2026: Umberto Veronesi Foundation ITALY – Evaluation of the Impact of Environmental Pollution on the Microbiota Immunity Axis in Colorectal Cancer Patients –Post-Doctoral Fellowship (Supervisor)
Past Projects 2020-2023
2020-2023: European Commission – Horizon 2020 – H2020-WIDESPREAD-2018-2020 – Project MICAfrica – Towards a North-African Consortium of the Human Microbiome (NACHM) through strengthening the Capacities in Microbiome Analysis for Human Diseases at University of Sfax (Partner)
2020-2021: Cassa di Risparmio di Firenze Foundation ITALY – Project – Goat’s milk obtained with a sustainable and guaranteed food strategy using thistle flour as an alternative protein source to soy: microbiota composition of milk and effects on the metabolism of human cancer and immune cells (Partner)
2020-2021: University of Florence – Project – HIV infection: The role of the microbiota and ethnicity in treatment (Principal Investigator)
2020-2021: Cassa di Risparmio di Firenze Foundation, ITALY – Project – Enhancement of synergistic local organic crops for the production of legumes, quality extra virgin olive oils and new nutraceuticals for well-being and the prevention of non-communicable pathologies or diseases (Partner)
2020-2021: Cassa di Risparmio di Firenze Foundation, ITALY – Project – Vaginal microbiome and blood markers of oxidative stress as non-invasive predictors of poor ovarian response in PMA: a strategy to reduce the “time to pregnancy” (Partner)
2020-2021: Cassa di Risparmio di Firenze Foundation, ITALY – Project – The gut/brain axis: the impact of Repetitive Transcranial Magnetic Stimulation (rTMS) and the intestinal microbiota in the treatment of cocaine addiction (Partner)
2020-2022: Italian Ministry of Health – Project – Abuse of immunotherapeutics in sport: development of a biosensor for myostatin inhibitors (Partner)
2020-2021: University of Florence – University funding for the acquisition of instruments aimed at research – Project – Acquisition of the nCounter Sprint Profiles instrument by Nanostring (Principal Investigator)
2021-2022: Cassa di Risparmio di Firenze Foundation, ITALY – Project – Inflammatory, chronic-degenerative and transmissible diseases: innovative strategies for the study of pathophysiology and the personalization of therapies (Partner)
2021-2022: University of Florence – Project – Characterisation of Tissue Microbiota: comparison of lung, colon and breast cancers (Principal Investigator)
2021-2022: Roche Foundation, ITALY– Project – Use of molecularly imprinted polymers as an alternative to current immunotherapy with antibodies in the treatment of rheumatoid arthritis (Partner)
2022-2023: University of Florence – Project – Breast cancer: differences in tumor microbiota between males and females (Principal Investigator)
Past Projects 2015-2020
2015-2016: Cassa di Risparmio di Firenze Foundation, ITALY – Project – Role of the PDIA3 protein in the tumor-specific response in patients with colorectal cancer (Partner)
2015-2016: University of Florence – Project – The role of the adaptive T response in patients with Barrett’s esophagus and/or pharyngeal adenocarcinoma (Partner)
2015-2017: Tuscany Region ITALY– FAS Health Projects – Project – Colorectal cancer: functional/metabolic characterization of the microbiota and the role of probiotics in modulating the specific immune response – MICpROBIMM – (Partner)
2017-2020: Por Fesr Marche ITALY – Project – Promote innovative solutions to address the challenges of local communities in the field of health and well-being through collaborative research and experimentation projects between companies and public/private structures that provide services to citizens – Probiosenior- (Partner)
2017-2018: Cassa di Risparmio di Firenze Foundation, ITALY – Project – Evaluation of the microbiota and miRNAs as disease biomarkers and related to treatment with probiotics/prebiotics in IBD patients (Principal Investigator)
2018-2021: Florentine University Funds for Doctorates in Clinical Sciences, ITALY – restricted thematic grant – multi-year strategic plan fund University of Florence 2018 – Project – Paleopathology: characterization of the human paleomicrobiome and immune response through the development of in silico interaction models (Principal Investigator)
2018-2019: Cassa di Risparmio di Firenze Foundation, ITALY – Project – New therapeutic perspectives with functional foods in patients with early diagnosis of systemic sclerosis: functional characterization of the different spatial structures of the microbiota (mouth, intestine and skin) and the associated immune response (Principal Investigator)
2018-2020: Cassa di Risparmio di Pistoia e Pescia Foundation, ITALY – Project – Pistoia flower nurseries: impact of the microbiota and the intestinal inflammatory response in the predisposition to weight gain and the risk of obesity (Coordinator)
2018-2022: Ministry of University and Research, ITALY Actively participates in the drafting of the project per i Departments of Excellence 2018-2022, won by the Department of Experimental and Experimental Medicine – International health cooperation in the field of health of migrants, ethnic minorities and host communities and traveller’s medicine (Travel Medicine) (Scientific Commitee Member)
2019-2021: Cassa di Risparmio di Firenze Foundation, ITALY – Project – New therapeutic perspectives with functional foods in patients with early diagnosis of systemic sclerosis: functional characterization of the different spatial structures of the microbiota (mouth, intestine and skin) and the associated immune response (Principal Investigator)
2019-2020: University of Florence – Project – HIV infection: The role of the microbiota and ethnicity in treatment (Partner)
Past Projects 2001-2015
2001-2002: University of Florence – Scientific programs for young researchers – Project – Relationships between immune response to Helicobacter pylori, atrophic gastritis and gastric adenocarcinoma (Principal Investigator)
2002-2003: University of Florence – Scientific programs for young researchers – Project – Natural and specific immunity to Helicobacter pylori in pediatric age (Partner)
2007-2009: PRIN: Scientific Research Programs of Significant National Interest: Unit scientific manager Research Project – Immunomodulatory activity in humans of products derived from persistent pathogens (Partner)
2007-2008: University of Florence – Project – Characterization of the specific T response to Mycobacterium paratuberculosis antigens in patients affected by Crohn’s disease (Principal Investigator)
2009-2010: Cassa di Risparmio di Pistoia e Pescia Foundation, ITALY– Project – Evaluation and enhancement of the specific T immune response to tumor antigens associated with gastric cancer: a new immunotherapeutic approach (Principal Investigator)
2009-2010: University of Florence– Project – Role and specificity of the cell-mediated response to viral antigens in the pathogenesis of Progressive Systemic Sclerosis (Principal Investigator)
2011-2013: PRIN: Scientific Research Programs of Significant National Interest: Unit scientific manager of the Project – Characterization of the human T immune response specific to new antigens associated with pancreatic cancer99 (Partner)
2012-2014: University of Florence – Project – Role of the PDIA3 protein in the tumor-specific response in patients with colorectal cancer” (Principal Investigator)