What is Mia-Lab

MIA-LAB is dedicated to studying the microbiome-immunity axis in human health, focusing on its role in the development of inflammation-related conditions such as cancer, autoimmune diseases, infections, and neurodegenerative disorders. In alignment with the concept of ``Circular Health,`` MIA-LAB emphasizes a holistic approach that recognizes humans as ``holobionts``—complex systems interconnected with their environment. To advance this vision, MIA-LAB has established a joint laboratory with partners of the Department of Experimental and Clinical Medicine and the Department of Agricultural, Food, Environmental, and Forestry Sciences and Technologies of the University of Florence, and the company Synbiotec Laboratories. The lab is committed to develop innovative analytical methods with versatile applications across clinical research, agri-food analysis, and agronomic practices. These initiatives aim to create cutting-edge diagnostic platforms that can be utilized in academic research, public institutions, and corporate settings at regional, national, and international levels, facilitating the design of new products and processes. By addressing dysregulation of the microbiota-immunity axis, MIA-LAB seeks to explore complex microbial ecosystems across human, animal, plant, and environmental niches. Its overarching goal is to contribute to global health improvement through integrative and effective approaches grounded in the principles of Circular Health.

Latest Funded Projects

Here you can find a preview of our latest funded project. More information is available at the `PROJECTS` page.

PROJECTS

Plastics monitoring detection remediation recovery funded by COST – European Cooperation in Science & Technology - CA20101

PRIORITY

Microbiota-Inflammation-Brain axis in heart failure: new food, biomarkerS and Approach for prevention of undernutrition in Older funded by Italian Ministry of University and Research under European Partnership ERA-NET ERA-HDHL Call 2020Horizon

AMBROSIA

Nano/microplastics effects on human health: transcriptional profiles, molecular pathways and inflammatory response associated with cell biology and microbiota dysfunction, funded by Italian Ministry of University and Research (MUR) under PRIN 2022.

PLAIORITY

A multiscale integrated approach to the study of the nervous system in health and disease, funded by European Union – NextGenerationEU under PNRR 2022

MNESYS

Microbiota-Inflammation-Brain axis in heart failure and inflammatory bowel disease: undernutrition prevention biomarkers and AI Approach , funded by European Union – NextGenerationEU under PNRR 2022

TUSCANY HEALTH ECOSYSTEM

Microbiome-immunity axis: functional food for the inflammation modulating in gastrointestinal diseases, funded by the University of Florence under “problem-driven" proposals to be carried out through the establishment of public-private partnerships within the framework of the PNRR

FONZIE

Neurosteroids against Neuroinflammation: a way to fight Neurodegeneration in Amyotrophic Lateral Sclerosis , unded by Italian Ministry of Health- Ricerca Finalizzata 2021

NEURALSTOP

Microorganisms, toxins and immunity intersection In amyotrophic lateralL Sclerosis and frontotemporal dementia: targeting disease Heterogeneity, funded by Italian Ministry of Health under PRIN PNRR 2022

MYSTICALS

Towards a North-African Consortium of the Human Microbiome (NACHM) through strengthening the Capacities in Microbiome Analysis for Human Diseases at University of Sfax, funded by the European Commission under Horizon 2020.

MICAfrica

Genetics and Environment intersection In the Amyotrophic Lateral Sclerosis - FrontoTemporal Dementia spectrum: an Italian Twins cohort study with a Multi-Omics approach - funded by Italian Ministry of Health under PNRR.

GENIALITY

Main Instruments

MagPix System

Streamlined imaging-based analyzer by Luminex that simultaneously measures up to 50 analytes in a single microplate well.

Ella Protein Simplex

Ella Protein Simplex by Biotechne is a next-generation benchtop automated ELISA platform that can assay up to 8 analytes simultaneously in less...

nCounter® Analysis

nCounter Nonostring technology multiplexes up to 800 gene expression targets using direct detection technology.

AutoMACS Pro

The autoMACS® NEO Separator is an automated cell separation, ideal for diverse downstream applications, such as flow cytometry, functional assays...

gentleMACS™ Octo Dissociator

gentleMACS™ Octo Dissociator provides automated and standardized tissue dissociation or homogenization of up to eight samples.

Agilent 4150 Tape Station

Electrophoresis System, DNA and RNA ScreenTape assays for application flexibility.

Publications

Explore our latest publications

Scopus Link

Our Team

About Us

Contact

MIA-Lab is located within f the Careggi University Hospital campus, at Padiglione 27, Centro Polivalente Cubo.
To get in touch, you can use the contact form or email us directly at the addresses listed on the About Us page.